李春权,男,1979年9月出生,博士,教授,博士生导师。南华大学计算机学院副院长,南华大学附属第一医院青年创新人才,省杰出青年基金获得者。中国计算机学会生物信息学专业委员会委员、中国抗癌协会肿瘤标志专业委员会肿瘤测序及大数据分析专家委员会委员、中国病理生理学会动脉粥样硬化专业委员会委员。获黑龙江省自然科学技术学术成果一等奖1项、哈尔滨市自然科学技术学术成果一等奖1项、哈尔滨市自然科学技术学术成果二等奖1项、大庆市然科学技术学术成果一等奖1项、大庆市科技进步一等奖1项。主持国家自然科学基金面上项目2项、国家自然科学基金青年项目1项、黑龙江省自然科学基金杰出青年项目1项、黑龙江省自然科学基金面上项目1项、博士后研究人员落户黑龙江科研启动资助项目1项、中国教育部,高等学校博士点学科专项科研基金项目1项、黑龙江省教育厅面上项目1项;参与国家自然科学基金委员会重大研究计划项目1项。近5年发表累计论文40余篇,多篇论文发表在《Nucleic Acids Research》、《Briefing in bioinformatics》、《Bioinformatics》、《Gastroenterolog》、《Nat Commun》等国际高影响力杂志上。Email:lcqbio@163.com。
李春权主要从事“复杂疾病的生物网络与通路的模型构建及分析方法研究”。通过结合医学大数据分析、机器学习、人工智能等技术方法,对癌症、心血管、糖尿病等各种复杂的重大疾病进行生物分子网络与通路的模型构建、数据库和软件平台开发、数据挖掘、分析方法研究。自主研发的SubpathwayMiner的子通路分析软件及由此软件衍生出的多款复杂疾病特异的通路网络分析软件和平台,被顶级综述杂志《Nature reviews cancer》(SCI影响因子=37.9)所引用,并且列入杂志论文的通路识别软件列表,被广泛推荐给各国的癌症研究人员使用;同时被列入的通路识别软件还有自主研发的GSEA、SPIA等软件。2011年SubpathwayMiner等相关软件平台被美国化学综述杂志《CHEMICAL REVIEWS》(SCI影响因子=40.2)、美国年度综述杂志《ANNUAL REVIEWS》(SCI影响因子=21.6)两大国际顶级杂志所引用和推荐研究人员使用。自主开发的SEdb超级增强子数据库,是目前世界上最全面的人类的超级增强子生物信息资源库,自主研发的SEanalysis在线软件分析平台,是超级增强子领域第一款基于web平台的在线超级增强子上下游调控网络分析工具。SEdb和SEanalysis平台目前已被美国、英国、德国、日本、法国等50个左右国家的研究机构研究者使用。
主持或参加科研项目及人才计划项目情况(按时间倒序排序):
v 国家自然科学基金委员会,面上项目,62171166,癌症超级增强子的上下游调控网络构建与分析方法研究,2022-01至2025-12,在研,主持。
v 南华大学,科研启动金,-,南华大学附属第一医院高层次人才科研启动金,2021-06至2028-06,在研,主持。
v 黑龙江省科学技术厅,省杰出青年科学基金项目,JQ2020C004,重大疾病中超级增强子的上游信号通路识别及调控机制研究,2020-7至2023-7,在研,主持。
v 黑龙江省人力资源和社会保障厅,博士后研究人员落户黑龙江科研启动资助金,复杂疾病中ncRNA调控的信号子通路的系统识别,2018-10至2020-12,已结题,主持。
v 国家自然科学基金委员会,面上项目,81572341,食管癌中非编码RNA调控的代谢通路高异常区域识别及其分子互作机制,2016-01至2019-12,已结题,主持。
v 黑龙江省自然科学基金委员会,面上项目,F2016031,整合microRNA与mRNA表达谱识别复杂疾病风险通路,2016-07至2019-07,已结题,主持。
v 国家自然科学基金委员会,青年项目,31401127,基于通路内部结构与通路间crosstalk识别复杂疾病风险通路的研究、2015-01至2017-12,已结题,参加。
v 哈尔滨医科大学,于维汉院士杰出青年培养基金项目,无,无,2014-07至2017-06,已结题,主持。
v 国家自然科学基金委员会,青年项目,31200996,整合高通量基因,代谢子和通路结构信息的癌症风险代谢通路区域系统识别,2013-01至2015-12,已结题,主持。
v 黑龙江省教育厅,面上项目,12531295,复杂疾病风险代谢通路整合识别方法研究,2013-01至2015-12,已结题,主持。
v 中国教育部,高等学校博士点学科专项科研基金项目(新教师基金课题),20102307120027,疾病代谢子通路融合挖掘及网络分析方法研究,2011-01至2013-12,已结题,主持。
v 黑龙江省教育厅,黑龙江省研究生创新基金(重点)项目,YJSCX2011-316HLJ,融合基因组和代谢组进行复杂疾病风险代谢通路区域精细识别,2011-09至2012-07,已结题,参加(申请人:李春权 ;项目负责人:导师 李霞教授)。
v 国家自然科学基金委员会,重大研究计划项目,91029717,融合组学挖掘非可控性炎症向癌症转化的分子机制,2011-01至2013-12,已结题,参加。
v 国家自然科学基金委员会,面上项目,30871394,复杂疾病关联的miRNA-mRNA功能模块识别的信息融合方法研究,2009-01至2011-12,已结题,参加。
近五年发表SCI论文
2022年:
1. Xu M#, Bai X, Ai B, Zhang G, Song C, Zhao J, Wang Y, Wei L, Qian F, Li Y, Zhou X, Zhou L, Yang Y, Chen J, Liu J, Shang D, Wang X, Zhao Y, Huang X, Zheng Y, Zhang J, Wang Q, Li C*. TF-Marker: a comprehensive manually curated database for transcription factors and related markers in specific cell and tissue types in human. Nucleic Acids Res. 2022 Jan 7;50(D1):D402-D412. doi: 10.1093/nar/gkab1114. PMID: 34986601; PMCID: PMC8728118.(SCI IF: 16.971)
2. Li Y#, Kong F, Cui H, Wang F, Li C, Ma J*. SENIES: DNA Shape Enhanced Two-layer Deep Learning Predictor for the Identification of Enhancers and Their Strength. IEEE/ACM Trans Comput Biol Bioinform. 2022 Jan 11;PP. doi: 10.1109/TCBB.2022.3142019. Epub ahead of print. PMID: 35015646.
3. Zhang Y, Song C, Zhang Y, Wang Y, Feng C, Chen J, Wei L, Pan Q, Shang D, Zhu Y, Zhu J, Fang S, Zhao J, Yang Y, Zhao X, Xu X, Wang Q, Guo J, Li C. TcoFBase: a comprehensive database for decoding the regulatory transcription co-factors in human and mouse. Nucleic Acids Res. 2022 Jan 7;50(D1):D391-D401. doi: 10.1093/nar/gkab950. PMID: 34718747; PMCID: PMC8728270.(SCI IF: 16.971)
2021年
4. Liu W, Xie L, He YH, Wu ZY, Liu LX, Bai XF, Deng DX, Xu XE, Liao LD, Lin W,Heng JH, Xu X, Peng L, Huang QF, Li CY, Zhang ZD, Wang W, Zhang GR, Gao X, Wang SH, Li CQ, Xu LY, Liu W, Li EM. Large-scale and high-resolution mass spectrometry-based proteomics profiling defines molecular subtypes of esophageal cancer for therapeutic targeting. Nat Commun. 2021 Aug 16;12(1):4961. doi: 10.1038/s41467-021-25202-5. PMID: 34400640; PMCID: PMC8368010.
5. Ding J, Li C, Cheng Y, Du Z, Wang Q, Tang Z, Song C, Xia Q, Bai W, Lin L, Liu W, Xu L, Li E, Wu B. Alterations of RNA splicing patterns in esophagus squamous cell carcinoma. Cell Biosci. 2021 Feb 9;11(1):36. doi: 10.1186/s13578-021-00546-z. PMID: 33563334; PMCID: PMC7871539.
6. Wei L, Chen J, Song C, Zhang Y, Zhang Y, Xu M, Feng C, Gao Y, Qian F, Wang Q, Shang D, Zhou X, Zhu J, Wang X, Jia Y, Liu J, Zhu Y, Li C. Cancer CRC: A Comprehensive Cancer Core Transcriptional Regulatory Circuit Resource and Analysis Platform. Front Oncol. 2021 Oct 12;11:761700. doi: 10.3389/fonc.2021.761700. PMID: 34712617; PMCID: PMC8546348.(SCI IF:6.244)
7. Chen S, Liu Q, Cui X, Feng Z, Li C, Wang X, Zhang X, Wang Y, Jiang R. OpenAnnotate: a web server to annotate the chromatin accessibility of genomic regions. Nucleic Acids Res. 2021 Jul 2;49(W1):W483-W490. doi: 10.1093/nar/gkab337. PMID: 33999180; PMCID: PMC8262705.(SCI IF: 16.971)
8. Chen J#, Zhang J#, Gao Y#, Li Y#, Feng C, Song C, Ning Z, Zhou X, Zhao J, Feng M, Zhang Y, Wei L, Pan Q, Jiang Y, Qian F, Han J, Yang Y, Wang Q, Li C*. LncSEA: a platform for long non-coding RNA related sets and enrichment analysis. Nucleic Acids Res. 2021 Jan 8;49(D1):D969-D980. doi: 10.1093/nar/gkaa806. PMID: 33045741; PMCID: PMC7778898.(SCI IF: 16.971)
9. Pan Q#, Liu YJ#, Bai XF#, Han XL#, Jiang Y, Ai B, Shi SS, Wang F, Xu MC, Wang YZ, Zhao J, Chen JX, Zhang J, Li XC, Zhu J, Zhang GR, Wang QY, Li CQ*. VARAdb: a comprehensive variation annotation database for human. Nucleic Acids Res. 2021 Jan 8;49(D1):D1431-D1444. doi: 10.1093/nar/gkaa922. PMID: 33095866; PMCID: PMC7779011.(SCI IF: 16.971)
10. Wang F#, Bai X#, Wang Y#, Jiang Y#, Ai B#, Zhang Y, Liu Y, Xu M, Wang Q, Han X, Pan Q, Li Y, Li X, Zhang J, Zhao J, Zhang G, Feng C, Zhu J, Li C*. ATACdb: a comprehensive human chromatin accessibility database. Nucleic Acids Res. 2021 Jan 8;49(D1):D55-D64. doi: 10.1093/nar/gkaa943. PMID: 33125076; PMCID: PMC7779059.(SCI IF: 16.971)
11. Fu Y, Sun C, Li Q, Qian F, Li C, Xi X, Shang D, Wang C, Peng X, Piao M, Qu W, Tian J, Yu B, Gu X, Tian J. Differential RNA expression profiles and competing endogenous RNA-associated regulatory networks during the progression of atherosclerosis. Epigenomics. 2021 Jan;13(2):99-112. doi: 10.2217/epi-2020-0252. Epub 2021 Jan 7. PMID: 33406894.
12. Li XC#, Tang ZD#, Peng L#, Li YY#, Qian FC, Zhao JM, Ding LW, Du XJ, Li M, Zhang J, Bai XF, Zhu J, Feng CC, Wang QY*, Pan J*, Li CQ*. Integrative Epigenomic Analysis of Transcriptional Regulation of Human CircRNAs. Front Genet. 2021 Jan 25;11:590672. doi: 10.3389/fgene.2020.590672. PMID: 33569079; PMCID: PMC7868561.
2020年:
13. Bai X#, Shi S#, Ai B#, Jiang Y#, Liu Y#, Han X, Xu M, Pan Q, Wang F, Wang Q, Zhang J, Li X, Feng C, Li Y, Wang Y, Song Y, Feng K, Li C*. ENdb: a manually curated database of experimentally supported enhancers for human and mouse. Nucleic Acids Res. 2020 Jan 8;48(D1):D51-D57. doi: 10.1093/nar/gkz973. PMID: 31665430. (SCI IF: 16.971)
14. Feng C#, Song C#, Liu Y#, Qian F, Gao Y, Ning Z, Wang Q, Jiang Y, Li Y, Li M, Chen J, Zhang J*, Li C*. KnockTF: a comprehensive human gene expression profile database with knockdown/knockout of transcription factors. Nucleic Acids Res. 2020 Jan 8;48(D1):D93-D100. doi: 10.1093/nar/gkz881. PMID: 31598675; PMCID:PMC6943067. (SCI IF: 16.971)
15. Li Y#, Li X#, Yang Y#, Li M#, Qian F, Tang Z, Zhao J, Zhang J, Bai X, Jiang Y, Zhou J, Zhang Y, Zhou L, Xie J, Li E, Wang Q*, Li C*. TRlnc: a comprehensive database for human transcriptional regulatory information of lncRNAs. Brief Bioinform. 2020 Feb 11. pii: bbaa011. doi: 10.1093/bib/bbaa011. [Epub ahead of print] PubMed PMID: 32047897. (SCI IF: IF=11.622)(2021.03)
16. Wang QY#, Peng L#, Chen Y, Liao LD, Chen JX, Li M, Li YY, Qian FC, Zhang YX, Wang F, Li CQ*, Lin DC*, Xu LY*, Li EM*. Characterization of super-enhancer-associated functional lncRNAs acting as ceRNAs in ESCC. Mol Oncol. 2020 Sep;14(9):2203-2230. doi: 10.1002/1878-0261.12726. Epub 2020 Jun 20. PMID:32460441; PMCID: PMC7463357.(SCI IF: 6.574)
17. Jiang YY#, Jiang Y#*, Li CQ#, Zhang Y#, Dakle P#, Kaur H, Deng JW, Lin RY, Han L, Xie JJ, Yan Y, Doan N, Zheng Y, Mayakonda A, Hazawa M, Xu L, Li Y, Aswad L, Jeitany M, Kanojia D, Guan XY, Said JW, Yang W, Fullwood MJ*, Lin DC*, Koeffler HP. TP63, SOX2, and KLF5 Establish a Core Regulatory Circuitry That Controls Epigenetic and Transcription Patterns in Esophageal Squamous Cell Carcinoma Cell Lines. Gastroenterology. 2020 Oct;159(4):1311-1327.e19. doi: 10.1053/j.gastro.2020.06.050. Epub 2020 Jun 30. PMID: 32619460.(SCI IF: 17. 373)
18. Guo-Wei H, Chun-Quan L, Lian-Di L, Ji-Wei J, Lin L, Ji-Yu D, Jin-Cheng G, En-Min L*, Li-Yan X*. LncRNA625 inhibits STAT1-mediated transactivation potential in esophageal cancer cells. Int J Biochem Cell Biol. 2019 Dec;117:105626. doi: 10.1016/j.biocel.2019.105626. Epub 2019 Oct 9. PMID: 31605752.
19. Liu W, Gan CY, Wang W, Liao LD, Li CQ, Xu LY*, Li EM*. Identification of lncRNA-associated differential subnetworks in oesophageal squamous cell carcinoma by differential co-expression analysis. J Cell Mol Med. 2020 Apr;24(8):4804-4818. doi: 10.1111/jcmm.15159. Epub 2020 Mar 12. PMID: 32164040; PMCID: PMC7176870.
20. Liu Y#, Cui Y#, Bai X#, Feng C, Li M, Han X, Ai B, Zhang J, Li X, Han J, Zhu J, Jiang Y, Pan Q, Wang F, Xu M, Li C, Wang Q*. MiRNA-Mediated Subpathway Identification and Network Module Analysis to Reveal Prognostic Markers in Human Pancreatic Cancer. Front Genet. 2020 Dec 9;11:606940. doi: 10.3389/fgene.2020.606940. PMID: 33362865; PMCID: PMC7756031.
21. Li M#, Zhao J#, Li X#, Chen Y, Feng C, Qian F, Liu Y, Zhang J, He J, Ai B, Ning Z, Liu W, Bai X, Han X, Wu Z, Xu X, Tang Z, Pan Q, Xu L, Li C*, Wang Q*, Li E*. HiFreSP: A novel high-frequency sub-pathway mining approach to identify robust prognostic gene signatures. Brief Bioinform. 2020 Jul 15;21(4):1411-1424. doi: 10.1093/bib/bbz078. PMID: 31350847.(SCI IF: IF=11.622)
2019年:
22. Qian FC#, Li XC#, Guo JC#, Zhao JM, Li YY, Tang ZD, Zhou LW, Zhang J, Bai XF, Jiang Y, Pan Q, Wang QY, Li EM, Li CQ*, Xu LY*, Lin DC*. SEanalysis: a web tool for super-enhancer associated regulatory analysis. Nucleic Acids Res. 2019 Jul 2;47(W1):W248-W255. doi: 10.1093/nar/gkz302. PubMed PMID: 31028388; PubMed Central PMCID: PMC6602466.(SCI IF::IF=16.971)
23. Ning Z#, Feng C#, Song C#, Liu W, Shang D, Li M, Wang Q, Zhao J, Liu Y, Chen J, Yu X*, Zhang J*, Li C*. Topologically inferring active miRNA-mediated subpathways toward precise cancer classification by directed random walk. Mol Oncol. 2019 Oct;13(10):2211-2226. doi: 10.1002/1878-0261.12563. Epub 2019 Aug 27. PubMed PMID: 31408573; PubMed Central PMCID: PMC676378. ( SCI IF: IF=5.962)
24. Zhao J#, Li X#, Guo J#, Li M, Zhang J, Ding J, Li S, Tang Z, Qian F, Li Y, Wang Q, Li C*, Li E*, Xu L*. ReCirc: prediction of circRNA expression and function through probe reannotation of non-circRNA microarrays. Mol Omics. 2019 Apr 1;15(2):150-163. doi: 10.1039/c8mo00252e. Epub 2019 Mar 27. PubMed PMID:30916068.
25. Peng L, Jiang B, Yuan X, Qiu Y, Peng J, Huang Y, Zhang C, Zhang Y, Lin Z, Li J, Yao W, Deng W, Zhang Y, Meng M, Pan X, Li C, Yin D, Bi X, Li G, Lin DC. Super-Enhancer-Associated Long Noncoding RNA HCCL5 Is Activated by ZEB1 and Promotes the Malignancy of Hepatocellular Carcinoma. Cancer Res. 2019 Feb 1;79(3):572-584. doi: 10.1158/0008-5472.CAN-18-0367. Epub 2018 Nov 27. PubMed PMID: 30482773.
26. Jiang Y#, Qian F#, Bai X#, Liu Y, Wang Q, Ai B, Han X, Shi S, Zhang J, Li X, Tang Z, Pan Q, Wang Y, Wang F, Li C*. SEdb: a comprehensive human super-enhancer database. Nucleic Acids Res. 2019 Jan 8;47(D1):D235-D243. doi: 10.1093/nar/gky1025. PubMed PMID: 30371817; PubMed Central PMCID: PMC6323980.(SCI IF: 16.971)
27. Tang Z#, Li X#, Zhao J#, Qian F, Feng C, Li Y, Zhang J, Jiang Y, Yang Y, Wang Q, Li C*. TRCirc: a resource for transcriptional regulation information of circRNAs. Brief Bioinform. 2019 Nov 27;20(6):2327-2333. doi: 10.1093/bib/bby083. PubMed PMID: 30184150.(SCI IF: 11.622)
2018年:
28. Feng C#, Song C#, Ning Z#, Ai B, Wang Q, Xu Y, Li M, Bai X, Zhao J, Liu Y, Li X, Zhang J*, Li C*. ce-Subpathway: Identification of ceRNA-mediated subpathways via joint power of ceRNAs and pathway topologies. J Cell Mol Med. 2019 Feb;23(2):967-984. doi: 10.1111/jcmm.13997. Epub 2018 Nov 12. PubMed PMID: 30421585; PubMed Central PMCID: PMC6349186.
29. Han J*#, Liu S#, Jiang Y#, Xu C#, Zheng B, Jiang M, Yang H, Su F, Li C*, Zhang Y*. Inference of patient-specific subpathway activities reveals a functional signature associated with the prognosis of patients with breast cancer. J Cell Mol Med. 2018 Sep;22(9):4304-4316. doi: 10.1111/jcmm.13720. Epub 2018 Jul 4. PubMed PMID: 29971923; PubMed Central PMCID: PMC6111825.
30. Zhang J#, Feng C#, Song C#, Ai B, Bai X, Liu Y, Li X, Zhao J, Shi S, Chen X, Su X*, Li C*. Identification and analysis of a key long non-coding RNAs (lncRNAs)-associated module reveal functional lncRNAs in cardiac hypertrophy. J Cell Mol Med. 2018 Feb;22(2):892-903.
31. Huang GW#, Xue YJ#, Wu ZY#, Xu XE, Wu JY, Cao HH, Zhu Y, He JZ, Li CQ, Li EM*, Xu LY*. A three-lncRNA signature predicts overall survival and disease-free survival in patients with esophageal squamous cell carcinoma. BMC Cancer. 2018 Feb 6;18(1):147. doi: 10.1186/s12885-018-4058-6. PubMed PMID: 29409459; PubMed Central PMCID: PMC5801805.
32. Jiang Y#, Jiang YY#*, Xie JJ#, Mayakonda A#, Hazawa M, Chen L, Xiao JF, Li CQ, Huang ML, Ding LW, Sun QY, Xu L, Kanojia D, Jeitany M, Deng JW, Liao LD, Soukiasian HJ, Berman BP, Hao JJ, Xu LY, Li EM, Wang MR, Bi XG, Lin DC*, Koeffler HP. Co-activation of super-enhancer-driven CCAT1 by TP63 and SOX2 promotes squamous cancer progression. Nat Commun. 2018 Sep 6;9(1):3619. doi: 10.1038/s41467-018-06081-9. PubMed PMID: 30190462.(SCI IF: 12.3)
33. Liu W#, He JZ#, Wang SH, Liu DK, Bai XF, Xu XE, Wu JY, Jiang Y, Li CQ, Chen LQ, Li EM*, Xu LY*. MASAN: a novel staging system for prognosis of patients withoesophageal squamous cell carcinoma. Br J Cancer. 2018 May 16. doi:10.1038/s41416-018-0094-x. [Epub ahead of print] PubMed PMID: 29765149.(SCI IF: 5.416)
2017年:
34. Zhang H#, Shang D#, Xu Y, Zhang C, Feng L, Sun Z, Shi X, Zhang Y, Han J, Su F, Li C*, Li X*. The LncRNA Connectivity Map: Using LncRNA Signatures to Connect Small Molecules, LncRNAs, and Diseases. Sci Rep. 2017 Jul 27;7(1):6655. doi: 10.1038/s41598-017-06897-3. PubMed PMID: 28751672; PubMed Central PMCID: PMC5532316.
35. Han J#, Liu S#, Sun Z, Zhang Y, Zhang F, Zhang C, Shang D, Yang H, Su F, Xu Y, Li C*, Ren H*, Li X*. LncRNAs2Pathways: Identifying the pathways influenced by a set of lncRNAs of interest based on a global network propagation method. Sci Rep. 2017 Apr 20;7:46566. doi: 10.1038/srep46566. PubMed PMID: 28425476; PubMed Central PMCID: PMC5397852.
36. Song C#, Zhang J#, Qi H#, Feng C, Chen Y, Cao Y, Ba L, Ai B, Wang Q, Huang W, Li C*, Sun H*. The global view of mRNA-related ceRNA cross-talks across cardiovascular diseases. Sci Rep. 2017 Aug 31;7(1):10185. doi: 10.1038/s41598-017-10547-z. PubMed PMID: 28860540; PubMed Central PMCID: PMC5579186.
37. Li C#*, Wang Q#*, Ma J#, Shi S, Chen X, Yang H, Han J*. Integrative Pathway Analysis of Genes and Metabolites Reveals Metabolism Abnormal Subpathway Regions and Modules in Esophageal Squamous Cell Carcinoma. Molecules. 2017 Sep 22;22(10). pii: E1599. doi: 10.3390/molecules22101599. PubMed PMID: 28937628 (IF=2.8)
38. Li CQ#, Huang GW#, Wu ZY#, Xu YJ, Li XC, Xue YJ, Zhu Y, Zhao JM, Li M, Zhang J, Wu JY, Lei F, Wang QY, Li S, Zheng CP, Ai B, Tang ZD, Feng CC, Liao LD, Wang SH, Shen JH, Liu YJ, Bai XF, He JZ, Cao HH, Wu BL, Wang MR, Lin DC, Koeffler HP, Wang LD, Li X*, Li EM*, Xu LY*. Integrative analyses of transcriptome sequencing identify novel functional lncRNAs in esophageal squamous cell carcinoma. Oncogenesis. 2017 Feb 13;6(2):e297. doi: 10.1038/oncsis.2017.1. PubMed PMID: 28194033; PubMed Central PMCID: PMC5337622. (SCI IF: 5.995)
39. Lin DC#*, Dinh HQ#, Xie JJ#*, Mayakonda A#, Silva TC, Jiang YY, Ding LW, He JZ, Xu XE, Hao JJ, Wang MR, Li C, Xu LY, Li EM*, Berman BP*, Phillip Koeffler H. Identification of distinct mutational patterns and new driver genes in oesophageal squamous cell carcinomas and adenocarcinomas. Gut. 2018 Oct;67(10):1769-1779. doi: 10.1136/gutjnl-2017-314607. Epub 2017 Aug 31. PubMed PMID: 28860350; PubMed Central PMCID: PMC5980794. (SCI IF: 16.6)
40. Zhan XH#, Jiao JW#, Zhang HF, Li CQ, Zhao JM, Liao LD, Wu JY, Wu BL, Wu ZY, Wang SH, Du ZP, Shen JH, Zou HY, Neufeld G, Xu LY*, Li EM*. A three-gene signature from protein-protein interaction network of LOXL2- and actin-related proteins for esophageal squamous cell carcinoma prognosis. Cancer Med. 2017 Jul;6(7):1707-1719. doi: 10.1002/cam4.1096. Epub 2017 May 29. PubMed PMID: 28556501; PubMed Central PMCID: PMC5504325.
41. 潘 奇,李 萌*,钱凤翠,汤治东,赵 越,王秋毓,李春权*. 整合基因的拷贝数与表达信息识别胶质瘤风险通路区域内的生存标志物. 《癌变、畸变、突变》,2017年1月,29卷,1期.